Monomethylamine (Methylamine, CH₃NH₂ in CH₃OH)

CAS No.: 74-89-5
   Synonyms / IUPAC Name: Monomethylamine; Methylamine
   Molecular Formula: CH₃NH₂ (solute) in CH₃OH (methanol)
   Molecular Weight (solute): 31.06 g/mol
   Appearance: Colourless to almost-colourless clear liquid solution
   Odor: Strong amine-like, fishy/alkaline smell

Physicochemical Properties (Typical)

• Specific Gravity: ~0.76 at 20 °C (typical 40 % in methanol solution)
• Solubility: Miscible with methanol; easily mixes in the solution medium
• Flash Point: Easily flammable due to methanol content and amine presence
• Vapour Pressure: Elevated due to volatile components; solution storage under inert gas recommended
• Stability: Sensitive to moisture and air; may degrade or release gases if improperly stored

Purity & Quality Standards

• Concentration: Technical grades ~30–40 % w/w monomethylamine in methanol solution
• Appearance: Clear solution, free from visible particulates
• Analytical Methods: Titration (neutralisation for amine content), GC for impurities, moisture and amine assay
• Documentation: Certificate of Analysis (COA) and Safety Data Sheet (SDS) supplied per batch

Applications / Uses

• Intermediate in chemical synthesis: manufacturing agrochemicals, pharmaceuticals, and speciality amines
• Building block for resins, surfactants, and other nitrogen-containing organic compounds
• Solvent/amine component in processes requiring both amine reactivity and methanol medium
• Laboratory reagent for research-scale synthesis in methanol solution form

Safety & Handling

• Classification: Highly flammable liquid and vapour; contains volatile amine with corrosive/irritant properties
• Health Hazards:
• Inhalation: May cause respiratory irritation, headache, dizziness
• Skin Contact: May cause irritation and absorption through skin barrier
• Eye Contact: Causes serious eye irritation and possible damage
• Precautions:
• Use in well-ventilated area or under local exhaust ventilation
• Wear protective gloves, eye/face protection, and suitable protective clothing
• Avoid heat, sparks, open flames, hot surfaces, and static discharge
• Reactivity / Incompatibilities: May react with strong oxidisers, acids, bases, certain metals; solution may evolve gas if improperly stored
• First Aid Measures:
• Inhalation: Move to fresh air, keep comfortable for breathing; seek medical attention if symptoms persist
• Skin Contact: Remove contaminated clothing; wash thoroughly with soap and water
• Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if present and safe to do; seek medical attention
• Ingestion: Rinse mouth; do not induce vomiting; seek immediate medical attention

Packaging & Storage

• Packaging: Sealed solvent-compatible containers suitable for flammable amine/methanol solutions (e.g., lined drums, sealed bottles)
• Storage Conditions: Cool (<30 °C), dry, well-ventilated area away from ignition sources, sunlight, and incompatible materials; inert gas blanketing may be required
• Container Closure: Keep tightly closed to prevent vapour release and contamination
• Shelf Life: Typically 12–24 months under recommended conditions; monitor for vapour evolution, pressure build-up or colour change